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A Free-Energy Approach for All-Atom Protein Simulation

All-atom free-energy methods offer a promising alternative to kinetic molecular mechanics simulations of protein folding and association. Here we report an accurate, transferable all-atom biophysical force field (PFF02) that stabilizes the native conformation of a wide range of proteins as the globa...

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Bibliografski detalji
Glavni autori: Verma, Abhinav, Wenzel, Wolfgang
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711412/
https://ncbi.nlm.nih.gov/pubmed/19413955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3921
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