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All-Atom Computer Simulations of Amyloid Fibrils Disaggregation

Amyloidlike fibrils are found in many fatal diseases, including Alzheimer's disease, type II diabetes mellitus, transmissible spongiform encephalopathies, and prion diseases. These diseases are linked to proteins that have partially unfolded, misfolded, and aggregated into amyloidlike fibrils....

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Bibliografiske detaljer
Main Authors: Wang, Jun, Tan, Chunhu, Chen, Hai-Feng, Luo, Ray
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586582/
https://ncbi.nlm.nih.gov/pubmed/18757563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131672
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