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Reparameterization of All-Atom Dipalmitoylphosphatidylcholine Lipid Parameters Enables Simulation of Fluid Bilayers at Zero Tension

Molecular dynamics simulations of dipalmitoylphosphatidylcholine (DPPC) lipid bilayers using the CHARMM27 force field in the tensionless isothermal-isobaric (NPT) ensemble give highly ordered, gel-like bilayers with an area per lipid of ∼48 Å(2). To obtain fluid (L(α)) phase properties of DPPC bilay...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sonne, Jacob, Jensen, Morten Ø., Hansen, Flemming Y., Hemmingsen, Lars, Peters, Günther H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877764/
https://ncbi.nlm.nih.gov/pubmed/17400696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.087130
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