Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models

Laminopathies encompass a wide array of human diseases associated to scattered mutations along LMNA, a single gene encoding A-type lamins. How such genetic alterations translate to cellular defects and generate such diverse disease phenotypes remains enigmatic. Recent work has identified nuclear env...

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Bibliographische Detailangaben
Hauptverfasser: Hale, Christopher M., Shrestha, Arun L., Khatau, Shyam B., Stewart-Hutchinson, P. J., Hernandez, Lidia, Stewart, Colin L., Hodzic, Didier, Wirtz, Denis
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2008
Schlagworte:
Cell Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586579/
https://ncbi.nlm.nih.gov/pubmed/18790843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.139428
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