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Potential Cation and H(+) Binding Sites in Acid Sensing Ion Channel-1
Acid sensing ion channels (ASICs) are cation-selective membrane channels activated by H(+) binding upon decrease in extracellular pH. It is known that Ca(2+) plays an important modulatory role in ASIC gating, competing with the ligand (H(+)) for its binding site(s). However, the H(+) or Ca(2+) bindi...
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| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Biophysical Society
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586576/ https://ncbi.nlm.nih.gov/pubmed/18790845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.141606 |
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