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Phosphorylation of SNAP-23 by IκB Kinase 2 Regulates Mast Cell Degranulation
Mast cells are known to play a pivotal role in allergic diseases. Cross-linking of the high-affinity receptor for IgE (FcεRI) leads to degranulation and allergic inflammation; however, the regulatory mechanisms of IgE-dependent exocytosis remain unknown. We show here that IκB kinase (IKK) 2 in mast...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586340/ https://ncbi.nlm.nih.gov/pubmed/18692471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.050 |
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