IκB kinase phosphorylation of SNAP-23 controls platelet secretion

Platelet secretion plays a key role in thrombosis, thus the platelet secretory machinery offers a unique target to modulate hemostasis. We report the regulation of platelet secretion via phosphorylation of SNAP-23 at Ser95. Phosphorylation of this t-soluble N-ethylmaleimide sensitive factor attachme...

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Detalhes bibliográficos
Main Authors: Karim, Zubair A., Zhang, Jinchao, Banerjee, Meenakshi, Chicka, Michael C., Al Hawas, Rania, Hamilton, Tara R., Roche, Paul A., Whiteheart, Sidney W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668489/
https://ncbi.nlm.nih.gov/pubmed/23613522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-470468
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