Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome

The construction of cDNA clones encoding large-size RNA molecules of biological interest, like coronavirus genomes, which are among the largest mature RNA molecules known to biology, has been hampered by the instability of those cDNAs in bacteria. Herein, we show that the application of two strategi...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Almazán, Fernando, González, José M., Pénzes, Zoltan, Izeta, Ander, Calvo, Enrique, Plana-Durán, Juan, Enjuanes, Luis
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC25860/
https://ncbi.nlm.nih.gov/pubmed/10805807
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы