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Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy

Although several autoimmune diseases are known to develop in postmenopausal women, the mechanisms by which estrogen deficiency influences autoimmunity remain unclear. Recently, we found that retinoblastoma-associated protein 48 (RbAp48) induces tissue-specific apoptosis in the exocrine glands depend...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ishimaru, Naozumi, Arakaki, Rieko, Yoshida, Satoko, Yamada, Akiko, Noji, Sumihare, Hayashi, Yoshio
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585852/
https://ncbi.nlm.nih.gov/pubmed/19015307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080174
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