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Cysteine-iron promotes arginase activity by driving the Fenton reaction
Impairment of nitric oxide bioavailability secondary to increased arginase activity and overproduction of reactive oxygen species (ROS) is thought to be a major cause of vascular complications in sickle cell disease (SCD). However, the role of ROS in the induction of arginase activity is unknown. Th...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585818/ https://ncbi.nlm.nih.gov/pubmed/18762165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.102 |
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