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Polyphosphate Functions In Vivo as an Iron Chelator and Fenton Reaction Inhibitor

Maintaining cellular iron homeostasis is critical for organismal survival. Whereas iron depletion negatively affects the many metabolic pathways that depend on the activity of iron-containing enzymes, any excess of iron can cause the rapid formation of highly toxic reactive oxygen species (ROS) thro...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Beaufay, François, Quarles, Ellen, Franz, Allison, Katamanin, Olivia, Wholey, Wei-Yun, Jakob, Ursula
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387796/
https://ncbi.nlm.nih.gov/pubmed/32723918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01017-20
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