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Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-α3 to antagonize Wnt/β-catenin signaling

Precise control of Wnt/β-catenin signaling is critical for animal development, stem cell renewal, and prevention of disease. In the fruit fly Drosophila melanogaster, the naked cuticle (nkd) gene limits signaling by the Wnt ligand Wingless (Wg) during embryo segmentation. Nkd is an intracellular pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chan, Chih-Chiang, Zhang, Shu, Rousset, Raphaël, Wharton, Keith A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585751/
https://ncbi.nlm.nih.gov/pubmed/18423435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.050
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