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Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-α3 to antagonize Wnt/β-catenin signaling

Precise control of Wnt/β-catenin signaling is critical for animal development, stem cell renewal, and prevention of disease. In the fruit fly Drosophila melanogaster, the naked cuticle (nkd) gene limits signaling by the Wnt ligand Wingless (Wg) during embryo segmentation. Nkd is an intracellular pro...

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Detalhes bibliográficos
Main Authors: Chan, Chih-Chiang, Zhang, Shu, Rousset, Raphaël, Wharton, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585751/
https://ncbi.nlm.nih.gov/pubmed/18423435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.050
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