Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-α3 to antagonize Wnt/β-catenin signaling

Precise control of Wnt/β-catenin signaling is critical for animal development, stem cell renewal, and prevention of disease. In the fruit fly Drosophila melanogaster, the naked cuticle (nkd) gene limits signaling by the Wnt ligand Wingless (Wg) during embryo segmentation. Nkd is an intracellular pro...

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Bibliographic Details
Main Authors: Chan, Chih-Chiang, Zhang, Shu, Rousset, Raphaël, Wharton, Keith A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585751/
https://ncbi.nlm.nih.gov/pubmed/18423435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.050
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