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Calorie restriction initiated at a young age activates the Akt/PKCζ/λ-Glut4 pathway in rat white adipose tissue in an insulin-independent manner

Calorie restriction (CR) may exert an anti-aging effect through a metabolic adaptation to limited energy intake. The present study investigated the effect of CR on insulin signaling in response to glucose load in the epididymal adipose tissue of male F344 rats at 7 and 22 months of age. Young and mi...

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Главные авторы: Park, Seongjoon, Komatsu, Toshimitsu, Hayashi, Hiroko, Yamaza, Haruyoshi, Chiba, Takuya, Higami, Yoshikazu, Kuramoto, Kazunao, Shimokawa, Isao
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585642/
https://ncbi.nlm.nih.gov/pubmed/19424853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-008-9071-2
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