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Calorie restriction initiated at a young age activates the Akt/PKCζ/λ-Glut4 pathway in rat white adipose tissue in an insulin-independent manner

Calorie restriction (CR) may exert an anti-aging effect through a metabolic adaptation to limited energy intake. The present study investigated the effect of CR on insulin signaling in response to glucose load in the epididymal adipose tissue of male F344 rats at 7 and 22 months of age. Young and mi...

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Main Authors: Park, Seongjoon, Komatsu, Toshimitsu, Hayashi, Hiroko, Yamaza, Haruyoshi, Chiba, Takuya, Higami, Yoshikazu, Kuramoto, Kazunao, Shimokawa, Isao
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585642/
https://ncbi.nlm.nih.gov/pubmed/19424853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-008-9071-2
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