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Neuropeptide Y resists excess loss of fat by lipolysis in calorie‐restricted mice: a trait potential for the life‐extending effect of calorie restriction

Neuropeptide Y (NPY) is an orexigenic peptide that plays an essential role in caloric restriction (CR)‐mediated lifespan extension. However, the mechanisms underlying the NPY‐mediated effects in CR are poorly defined. Here, we report that NPY deficiency in male mice during CR increases mortality in...

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Publicat a:Aging Cell
Autors principals: Park, Seongjoon, Komatsu, Toshimitsu, Kim, Sang Eun, Tanaka, Katsuya, Hayashi, Hiroko, Mori, Ryoichi, Shimokawa, Isao
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334538/
https://ncbi.nlm.nih.gov/pubmed/28101970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12558
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