Neuropeptide Y resists excess loss of fat by lipolysis in calorie‐restricted mice: a trait potential for the life‐extending effect of calorie restriction

Neuropeptide Y (NPY) is an orexigenic peptide that plays an essential role in caloric restriction (CR)‐mediated lifespan extension. However, the mechanisms underlying the NPY‐mediated effects in CR are poorly defined. Here, we report that NPY deficiency in male mice during CR increases mortality in...

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Publicado en:Aging Cell
Main Authors: Park, Seongjoon, Komatsu, Toshimitsu, Kim, Sang Eun, Tanaka, Katsuya, Hayashi, Hiroko, Mori, Ryoichi, Shimokawa, Isao
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334538/
https://ncbi.nlm.nih.gov/pubmed/28101970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12558
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