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Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
Familial amyotrophic lateral sclerosis (fALS) caused by mutations in copper–zinc superoxide dismutase (SOD1) is characterized by the presence of SOD1-rich inclusions in spinal cords. Similar inclusions observed in fALS transgenic mice have a fibrillar appearance suggestive of amyloid structure. Meta...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585484/ https://ncbi.nlm.nih.gov/pubmed/19022905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807058105 |
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