IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis

BACKGROUND: Vascular endothelial growth factor receptor-2 (VEGFR-2) signaling is an obligate requirement for normal development and pathological angiogenesis such as cancer and age-related macular degeneration. Although autophosphorylation of tyrosine 1173 (Y1173) of VEGFR-2 is considered a focal po...

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Bibliografiska uppgifter
Huvudupphovsmän: Meyer, Rosana D., Sacks, David B., Rahimi, Nader
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2008
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585478/
https://ncbi.nlm.nih.gov/pubmed/19050761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003848
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