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Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

Transendothelial migration (TEM) of leukocytes across the endothelium is critical for inflammation. In the endothelium, TEM requires the coordination of membrane movements and cytoskeletal interactions, including, prominently, recruitment of the lateral border recycling compartment (LBRC). The scaff...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Sullivan, David P., Dalal, Prarthana J., Jaulin, Fanny, Sacks, David B., Kreitzer, Geri, Muller, William A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829592/
https://ncbi.nlm.nih.gov/pubmed/31395618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190008
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