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Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

Transendothelial migration (TEM) of leukocytes across the endothelium is critical for inflammation. In the endothelium, TEM requires the coordination of membrane movements and cytoskeletal interactions, including, prominently, recruitment of the lateral border recycling compartment (LBRC). The scaff...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Sullivan, David P., Dalal, Prarthana J., Jaulin, Fanny, Sacks, David B., Kreitzer, Geri, Muller, William A.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829592/
https://ncbi.nlm.nih.gov/pubmed/31395618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190008
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