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BP1 motif in the human β-globin promoter affects β-globin expression during embryonic/fetal erythropoiesis in transgenic mice bearing the human β-globin gene

The binding of the transcription factor BP1 (β protein 1) to its site on the promoter of the adult β-globin gene has a silencing effect on β-globin transcription in vitro. To better understand the mechanism of BP1’s negative regulation of β-globin expression, we developed transgenic mice bearing a h...

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Bibliografiske detaljer
Main Authors: Zoueva, Olga P., Garrett, Lisa J., Bodine, David, Rodgers, Griffin P.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585064/
https://ncbi.nlm.nih.gov/pubmed/18656399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2008.05.008
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