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BP1 motif in the human β-globin promoter affects β-globin expression during embryonic/fetal erythropoiesis in transgenic mice bearing the human β-globin gene
The binding of the transcription factor BP1 (β protein 1) to its site on the promoter of the adult β-globin gene has a silencing effect on β-globin transcription in vitro. To better understand the mechanism of BP1’s negative regulation of β-globin expression, we developed transgenic mice bearing a h...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585064/ https://ncbi.nlm.nih.gov/pubmed/18656399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2008.05.008 |
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