EKLF and KLF2 have compensatory roles in embryonic β-globin gene expression and primitive erythropoiesis

The Krüppel-like C2/H2 zinc finger transcription factors (KLFs) control development and differentiation. Erythroid Krüppel-like factor (EKLF or KLF1) regulates adult β-globin gene expression and is necessary for normal definitive erythropoiesis. KLF2 is required for normal embryonic Ey- and βh1-, bu...

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Detalhes bibliográficos
Main Authors: Basu, Priyadarshi, Lung, Tina K., Lemsaddek, Wafaa, Sargent, Thanh Giang, Williams, David C., Basu, Mohua, Redmond, Latasha C., Lingrel, Jerry B, Haar, Jack L., Lloyd, Joyce A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Red Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200909/
https://ncbi.nlm.nih.gov/pubmed/17675555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-057307
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