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EKLF and KLF2 have compensatory roles in embryonic β-globin gene expression and primitive erythropoiesis
The Krüppel-like C2/H2 zinc finger transcription factors (KLFs) control development and differentiation. Erythroid Krüppel-like factor (EKLF or KLF1) regulates adult β-globin gene expression and is necessary for normal definitive erythropoiesis. KLF2 is required for normal embryonic Ey- and βh1-, bu...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200909/ https://ncbi.nlm.nih.gov/pubmed/17675555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-057307 |
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