Inhibition of Na(+)/H(+) exchanger enhances low pH-induced L-selectin shedding and β(2)-integrin surface expression in human neutrophils

Ischemia-reperfusion injury is a common pathological occurrence causing tissue damage in heart attack and stroke. Entrapment of neutrophils in the vasculature during ischemic events has been implicated in this process. In this study, we examine the effects that lactacidosis and consequent reductions...

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Autori principali: Kaba, Nubia K., Schultz, Joanne, Law, Foon-Yee, Lefort, Craig T., Martel-Gallegos, Guadalupe, Kim, Minsoo, Waugh, Richard E., Arreola, Jorge, Knauf, Philip A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584992/
https://ncbi.nlm.nih.gov/pubmed/18829897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00535.2007
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