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Effect of Extracellular pH on Selectin Adhesion: Theory and Experiment

Selectins mediate circulatory leukocyte trafficking to sites of inflammation and trauma, and the extracellular microenvironments at these sites often become acidic. In this study, we investigated the influence of slightly acidic pH on the binding dynamics of selectins (P-, L-, and E-selectin) to P-s...

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Autors principals: Cao, Thong M., Takatani, Tait, King, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552277/
https://ncbi.nlm.nih.gov/pubmed/23442851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.005
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