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Effect of Extracellular pH on Selectin Adhesion: Theory and Experiment
Selectins mediate circulatory leukocyte trafficking to sites of inflammation and trauma, and the extracellular microenvironments at these sites often become acidic. In this study, we investigated the influence of slightly acidic pH on the binding dynamics of selectins (P-, L-, and E-selectin) to P-s...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552277/ https://ncbi.nlm.nih.gov/pubmed/23442851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.005 |
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