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Effect of Extracellular pH on Selectin Adhesion: Theory and Experiment

Selectins mediate circulatory leukocyte trafficking to sites of inflammation and trauma, and the extracellular microenvironments at these sites often become acidic. In this study, we investigated the influence of slightly acidic pH on the binding dynamics of selectins (P-, L-, and E-selectin) to P-s...

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Detalles Bibliográficos
Main Authors: Cao, Thong M., Takatani, Tait, King, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552277/
https://ncbi.nlm.nih.gov/pubmed/23442851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.005
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