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Inhibition of Na(+)/H(+) exchanger enhances low pH-induced L-selectin shedding and β(2)-integrin surface expression in human neutrophils

Ischemia-reperfusion injury is a common pathological occurrence causing tissue damage in heart attack and stroke. Entrapment of neutrophils in the vasculature during ischemic events has been implicated in this process. In this study, we examine the effects that lactacidosis and consequent reductions...

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Hlavní autoři: Kaba, Nubia K., Schultz, Joanne, Law, Foon-Yee, Lefort, Craig T., Martel-Gallegos, Guadalupe, Kim, Minsoo, Waugh, Richard E., Arreola, Jorge, Knauf, Philip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584992/
https://ncbi.nlm.nih.gov/pubmed/18829897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00535.2007
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