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How strict is the correlation between STIM1 and Orai1 expression, puncta formation, and I(CRAC) activation?

Stromal interaction molecule 1 (STIM1) and Orai1 have been identified as crucial elements of the store-operated Ca(2+) entry (SOCE) pathway, but the mechanism of their functional interaction remains controversial. It is now well established that, upon depletion of the stores, both molecules can accu...

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Autori principali: Gwozdz, Tomasz, Dutko-Gwozdz, Joanna, Zarayskiy, Vladislav, Peter, Krisztina, Bolotina, Victoria M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584986/
https://ncbi.nlm.nih.gov/pubmed/18768920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00306.2008
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