Novel Role for STIM1 as a Trigger for Calcium Influx Factor Production

STIM1 has been recently identified as a Ca(2+) sensor in endoplasmic reticulum (ER) and an initiator of the store-operated Ca(2+) entry (SOCE) pathway, but the mechanism of SOCE activation remains controversial. Here we focus on the early ER-delimited steps of the SOCE pathway and demonstrate that S...

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Hauptverfasser: Csutora, Peter, Peter, Krisztina, Kilic, Helena, Park, Kristen M., Zarayskiy, Vladislav, Gwozdz, Tomasz, Bolotina, Victoria M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Mechanisms of Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386937/
https://ncbi.nlm.nih.gov/pubmed/18337241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709575200
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