Periostin induces proliferation of human autosomal dominant polycystic kidney cells through α(V)-integrin receptor

Progressive renal enlargement due to the growth of innumerable fluid-filled cysts is a central pathophysiological feature of autosomal dominant polycystic kidney disease (ADPKD). These epithelial neoplasms enlarge slowly and damage noncystic parenchyma by mechanisms that have not been clearly define...

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Main Authors: Wallace, Darren P., Quante, Megan T., Reif, Gail A., Nivens, Emily, Ahmed, Farhana, Hempson, Scott J., Blanco, Gustavo, Yamaguchi, Tamio
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584901/
https://ncbi.nlm.nih.gov/pubmed/18753297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90266.2008
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