cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells

The goal of this study was to identify a mechanism regulating cholesterol accumulation in cystic fibrosis (CF) cells. Both CFTR activation and expression are regulated by the cAMP pathway, and it is hypothesized that a feedback response involving this pathway may be involved in the phenotype of chol...

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Bibliographic Details
Main Authors: Manson, Mary E., Corey, Deborah A., White, Nicole M., Kelley, Thomas J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584893/
https://ncbi.nlm.nih.gov/pubmed/18790990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90402.2008
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