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cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells
The goal of this study was to identify a mechanism regulating cholesterol accumulation in cystic fibrosis (CF) cells. Both CFTR activation and expression are regulated by the cAMP pathway, and it is hypothesized that a feedback response involving this pathway may be involved in the phenotype of chol...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584893/ https://ncbi.nlm.nih.gov/pubmed/18790990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90402.2008 |
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