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Regulatory role of β-arrestin-2 in cholesterol processing in cystic fibrosis epithelial cells

Cystic fibrosis (CF) cells exhibit an increase in the protein expression of β-arrestin-2 (βarr2) coincident with perinuclear accumulation of free cholesterol. Arrestins are proteins that both serve as broad signaling regulators and contribute to G-protein coupled receptor internalization after agoni...

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Bibliografiska uppgifter
Huvudupphovsmän: Manson, Mary E., Corey, Deborah A., Bederman, Ilya, Burgess, James D., Kelley, Thomas J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371238/
https://ncbi.nlm.nih.gov/pubmed/22523395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021972
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