Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis

BACKGROUND: Previous observations demonstrate that Cftr-null cells and tissues exhibit alterations in cholesterol processing including perinuclear cholesterol accumulation, increased de novo synthesis, and an increase in plasma membrane cholesterol accessibility compared to wild type controls. The h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fang, Danjun, West, Richard H, Manson, Mary E, Ruddy, Jennifer, Jiang, Dechen, Previs, Stephen F, Sonawane, Nitin D, Burgess, James D, Kelley, Thomas J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880018/
https://ncbi.nlm.nih.gov/pubmed/20487541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-61
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados