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Regulatory role of β-arrestin-2 in cholesterol processing in cystic fibrosis epithelial cells
Cystic fibrosis (CF) cells exhibit an increase in the protein expression of β-arrestin-2 (βarr2) coincident with perinuclear accumulation of free cholesterol. Arrestins are proteins that both serve as broad signaling regulators and contribute to G-protein coupled receptor internalization after agoni...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371238/ https://ncbi.nlm.nih.gov/pubmed/22523395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021972 |
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