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Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase η in translesion DNA synthesis
Treatment of yeast and human cells with DNA-damaging agents elicits Rad6–Rad18-mediated monoubiquitination of proliferating cell nuclear antigen (PCNA) at its Lys-164 residue [ubiquitin (Ub)-PCNA], and this PCNA modification is indispensable for promoting the access of translesion synthesis (TLS) po...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584706/ https://ncbi.nlm.nih.gov/pubmed/19001268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809844105 |
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