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Highly potent, fully recombinant anti-HIV chemokines: Reengineering a low-cost microbicide

New prevention strategies for use in developing countries are urgently needed to curb the worldwide HIV/AIDS epidemic. The N-terminally modified chemokine PSC-RANTES is a highly potent entry inhibitor against R5-tropic HIV-1 strains, with an inhibitory mechanism involving long-term intracellular seq...

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Autors principals: Gaertner, Hubert, Cerini, Fabrice, Escola, Jean-Michel, Kuenzi, Gabriel, Melotti, Astrid, Offord, Robin, Rossitto-Borlat, Irène, Nedellec, Rebecca, Salkowitz, Janelle, Gorochov, Guy, Mosier, Donald, Hartley, Oliver
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584686/
https://ncbi.nlm.nih.gov/pubmed/19004761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805098105
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