Human Immunodeficiency Virus Type 1 Entry Inhibitors Selected on Living Cells from a Library of Phage Chemokines

The chemokine receptors CCR5 and CXCR4 are promising non-virus-encoded targets for human immunodeficiency virus (HIV) therapy. We describe a selection procedure to isolate mutant forms of RANTES (CCL5) with antiviral activity considerably in excess of that of the native chemokine. The phage-displaye...

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Detaylı Bibliyografya
Asıl Yazarlar: Hartley, Oliver, Dorgham, Karim, Perez-Bercoff, Danielle, Cerini, Fabrice, Heimann, Anouk, Gaertner, Hubert, Offord, Robin E., Pancino, Gianfranco, Debré, Patrice, Gorochov, Guy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2003
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC156188/
https://ncbi.nlm.nih.gov/pubmed/12767983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6637-6644.2003
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