Human Immunodeficiency Virus Type 1 Entry Inhibitors Selected on Living Cells from a Library of Phage Chemokines

The chemokine receptors CCR5 and CXCR4 are promising non-virus-encoded targets for human immunodeficiency virus (HIV) therapy. We describe a selection procedure to isolate mutant forms of RANTES (CCL5) with antiviral activity considerably in excess of that of the native chemokine. The phage-displaye...

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Detalhes bibliográficos
Main Authors: Hartley, Oliver, Dorgham, Karim, Perez-Bercoff, Danielle, Cerini, Fabrice, Heimann, Anouk, Gaertner, Hubert, Offord, Robin E., Pancino, Gianfranco, Debré, Patrice, Gorochov, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156188/
https://ncbi.nlm.nih.gov/pubmed/12767983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6637-6644.2003
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