Human Immunodeficiency Virus Type 1 Entry Inhibitors Selected on Living Cells from a Library of Phage Chemokines

The chemokine receptors CCR5 and CXCR4 are promising non-virus-encoded targets for human immunodeficiency virus (HIV) therapy. We describe a selection procedure to isolate mutant forms of RANTES (CCL5) with antiviral activity considerably in excess of that of the native chemokine. The phage-displaye...

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Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Hartley, Oliver, Dorgham, Karim, Perez-Bercoff, Danielle, Cerini, Fabrice, Heimann, Anouk, Gaertner, Hubert, Offord, Robin E., Pancino, Gianfranco, Debré, Patrice, Gorochov, Guy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156188/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12767983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6637-6644.2003
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