Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
When the heart fails, there is often a constellation of biochemical alterations of the β-adrenergic receptor (βAR) signaling system, leading to the loss of cardiac inotropic reserve. βAR down-regulation and functional uncoupling are mediated through enhanced activity of the βAR kinase (βARK1), the e...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090091197 |
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