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Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
Chronic human heart failure is characterized by abnormalities in β-adrenergic receptor (βAR) signaling, including increased levels of βAR kinase 1 (βARK1), which seems critical to the pathogenesis of the disease. To determine whether inhibition of βARK1 is sufficient to rescue a model of severe hear...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33295/ https://ncbi.nlm.nih.gov/pubmed/11331748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091102398 |
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