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Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction

When the heart fails, there is often a constellation of biochemical alterations of the β-adrenergic receptor (βAR) signaling system, leading to the loss of cardiac inotropic reserve. βAR down-regulation and functional uncoupling are mediated through enhanced activity of the βAR kinase (βARK1), the e...

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Bibliografiske detaljer
Main Authors: White, David C., Hata, Jonathan A., Shah, Ashish S., Glower, Donald D., Lefkowitz, Robert J., Koch, Walter J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25845/
https://ncbi.nlm.nih.gov/pubmed/10779554
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