Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human β-globin in engrafted mice

Lignende værker

• Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure.
  af: Leboulch, P, et al.
  Udgivet: (1994)
• High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells
  af: Imren, Suzan, et al.
  Udgivet: (2004)
• Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease.
  af: Takekoshi, K J, et al.
  Udgivet: (1995)
• Permanent and panerythroid correction of murine β thalassemia by multiple lentiviral integration in hematopoietic stem cells
  af: Imren, Suzan, et al.
  Udgivet: (2002)
• Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates
  af: Takatoku, Masaaki, et al.
  Udgivet: (2001)