Permanent and panerythroid correction of murine β thalassemia by multiple lentiviral integration in hematopoietic stem cells

Achieving long-term pancellular expression of a transferred gene at therapeutic level in a given hematopoietic lineage remains an important goal of gene therapy. Advances have recently been made in the genetic correction of the hemoglobinopathies by means of lentiviral vectors and large locus contro...

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Bibliografische gegevens
Hoofdauteurs: Imren, Suzan, Payen, Emmanuel, Westerman, Karen A., Pawliuk, Robert, Fabry, Mary E., Eaves, Connie J., Cavilla, Benjamin, Wadsworth, Louis D., Beuzard, Yves, Bouhassira, Eric E., Russell, Robert, London, Irving M., Nagel, Ronald L., Leboulch, Philippe, Humphries, R. Keith
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2002
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137892/
https://ncbi.nlm.nih.gov/pubmed/12391330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212507099
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