Biochemical Characterization of a Recombinant TRIM5α Protein That Restricts Human Immunodeficiency Virus Type 1 Replication

The rhesus monkey intrinsic immunity factor TRIM5α(rh) recognizes incoming capsids from a variety of retroviruses, including human immunodeficiency virus type 1 (HIV-1) and equine infectious anemia virus (EIAV), and inhibits the accumulation of viral reverse transcripts. However, direct interactions...

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Detalhes bibliográficos
Main Authors: Langelier, Charles R., Sandrin, Virginie, Eckert, Debra M., Christensen, Devin E., Chandrasekaran, Viswanathan, Alam, Steven L., Aiken, Christopher, Olsen, John C., Kar, Alak Kanti, Sodroski, Joseph G., Sundquist, Wesley I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583683/
https://ncbi.nlm.nih.gov/pubmed/18799573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01562-08
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