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Identification of Human MVB12 Proteins as ESCRT-I Subunits that Function in HIV Budding

Human ESCRT-I is a multiprotein complex that plays essential roles in HIV budding and endosomal protein sorting. All ESCRT-I complexes contain three common subunits (TSG101, VPS28, and VPS37), and a fourth subunit of yeast ESCRT-I was recently identified (Mvb12p). We now demonstrate that two related...

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Detalhes bibliográficos
Main Authors: Morita, Eiji, Sandrin, Virginie, Alam, Steven L., Eckert, Debra M., Gygi, Steven P., Sundquist, Wesley I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034311/
https://ncbi.nlm.nih.gov/pubmed/18005716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.06.003
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