Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism

Chronic viral infection is characterized by the functional impairment of virus-specific T-cell responses. Recent evidence has suggested that the inhibitory receptor programmed death 1 (PD-1) is specifically upregulated on antigen-specific T cells during various chronic viral infections. Indeed, it h...

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Main Authors: Muthumani, Karuppiah, Choo, Andrew Y., Shedlock, Devon J., Laddy, Dominick J., Sundaram, Senthil G., Hirao, Lauren, Wu, Ling, Thieu, Khanh P., Chung, Christopher W., Lankaraman, Karthikbabu M., Tebas, Pablo, Silvestri, Guido, Weiner, David B.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
主題:
Pathogenesis and Immunity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583658/
https://ncbi.nlm.nih.gov/pubmed/18799583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00485-08
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