Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism

Chronic viral infection is characterized by the functional impairment of virus-specific T-cell responses. Recent evidence has suggested that the inhibitory receptor programmed death 1 (PD-1) is specifically upregulated on antigen-specific T cells during various chronic viral infections. Indeed, it h...

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Detalhes bibliográficos
Main Authors: Muthumani, Karuppiah, Choo, Andrew Y., Shedlock, Devon J., Laddy, Dominick J., Sundaram, Senthil G., Hirao, Lauren, Wu, Ling, Thieu, Khanh P., Chung, Christopher W., Lankaraman, Karthikbabu M., Tebas, Pablo, Silvestri, Guido, Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583658/
https://ncbi.nlm.nih.gov/pubmed/18799583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00485-08
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